Immuno-Activated, Highly Expressing PD-1 Phenotype in Hepatocellular Carcinoma Is Associated with a Lower Recurrence Rate
PD-1 expression on immune cells is associated with a lower recurrence rate in HCC, suggesting a role in HCC recurrence. The therapeutic use of adjuvant anti-PD-1 antibodies should thus be viewed critically and investigated further.
Authors
- Gabriel Fridolin Hess (ORCID: https://orcid.org/0000-0001-8644-8292)
- Luigi Terracciano (ORCID: https://orcid.org/0000-0002-9393-9660)
- Silvio Däster (ORCID: https://orcid.org/0000-0001-5188-4908)
- Otto Kollmar (ORCID: https://orcid.org/0000-0003-4558-4006)
- Mairene Coto‐Llerena (ORCID: https://orcid.org/0000-0001-7596-1250)
- Caner Ercan
- Salvatore Piscuoglio (ORCID: https://orcid.org/0000-0003-2686-2939)
- Simone E. Muenst (ORCID: https://orcid.org/0000-0001-7973-1401)
- Jürg Vosbeck
- Savas D. Soysal (ORCID: https://orcid.org/0000-0002-0761-449X)
- Alexander Wilhelm (ORCID: https://orcid.org/0000-0001-9496-0237)
- Martin Bolli (ORCID: https://orcid.org/0000-0003-2676-6322)
- Jasmin Zeindler (ORCID: https://orcid.org/0000-0002-5400-7844)
Institutions
- Humanitas University (IT)
- University of Basel (CH)
- University Hospital of Basel (CH)
- Department of Biomedicine Basel (CH)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- Pathobiology
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1159/000543933
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00