Opioid therapy vs. Multimodal analgesia in head and neck cancer (OPTIMAL-HN): Results of a randomized clinical trial
MMA demonstrates non-inferiority to opioid analgesia alone in managing RIM pain during the last week of RT and superiority when analyzing the post-RT time period. MMA should, therefore, be considered an effective mode of analgesia for HNC patients receiving RT.
Authors
- Krista D’Angelo
- C.D. Goodman (ORCID: https://orcid.org/0000-0002-8923-7594)
- Caitlin Carreau
- Nancy Read
- Danielle Vanwynsberghe
- Rohann Correa (ORCID: https://orcid.org/0000-0003-0886-1625)
- Eric Winquist (ORCID: https://orcid.org/0000-0002-8829-5979)
- Dwight E. Moulin (ORCID: https://orcid.org/0000-0001-9902-2418)
- Pencilla Lang (ORCID: https://orcid.org/0000-0003-3156-4450)
- Sondos Zayed (ORCID: https://orcid.org/0000-0002-3525-7469)
- Adam Mutsaers (ORCID: https://orcid.org/0000-0002-2185-6874)
- Paul Stewart (ORCID: https://orcid.org/0000-0002-2660-0544)
- David A. Palma (ORCID: https://orcid.org/0000-0002-9542-0627)
- Kelsey Kieraszewicz
- Alika Kingsbury-Paul
- Sara Kuruvilla
- Kathlin Crewdson
- Andrew Warner
- Jennifer Neeb
Institutions
- Western University (CA)
- University of Ottawa (CA)
- Ottawa Hospital (CA)
- London Health Sciences Centre (CA)
Publication Details
- Journal
- Radiotherapy and Oncology
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1016/j.radonc.2025.110831
- Citations
- 1
- Primary Topic
- Oral health in cancer treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52