Effectiveness of Ampicillin-Sulbactam Versus Ceftriaxone for the Initial Treatment of Community-Acquired Pneumonia in Older Adults: A Target Trial Emulation Study

In older patients with CAP, initial treatment with ampicillin-sulbactam was associated with higher mortality compared to treatment with ceftriaxone.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2025-02-28
DOI
https://doi.org/10.1093/ofid/ofaf133
Citations
5
Primary Topic
Pneumonia and Respiratory Infections
Type
article
Field-Weighted Citation Impact
6.77
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article

Effectiveness of Ampicillin-Sulbactam Versus Ceftriaxone for the Initial Treatment of Community-Acquired Pneumonia in Older Adults: A Target Trial Emulation Study

Akihiro Shiroshita, Shungo Yamamoto, Yuki Kataoka, Hidehiro Someko
5 citations
Open Forum Infectious Diseases
Pneumonia and Respiratory Infections
6.77
article

Effectiveness of Ampicillin-Sulbactam Versus Ceftriaxone for the Initial Treatment of Community-Acquired Pneumonia in Older Adults: A Target Trial Emulation Study

Akihiro Shiroshita, Shungo Yamamoto, Yuki Kataoka, Hidehiro Someko
article en
5 citations

Abstract

In older patients with CAP, initial treatment with ampicillin-sulbactam was associated with higher mortality compared to treatment with ceftriaxone.

Open Forum Infectious DiseasesVol. 12(3)
Vanderbilt University (US), Kyoto University (JP), Kyoto University Hospital (JP), Osaka University Hospital (JP), Scientific Research WorkS Peer Support Group, The University of Osaka (JP)
Good health and well-being
Openalex Percentile: Top 3%
Pneumonia and Respiratory Infections
6.77
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Effectiveness of Ampicillin-Sulbactam Versus Ceftriaxone for the Initial Treatment of Community-Acquired Pneumonia in Older Adults: A Target Trial Emulation Study — Akihiro Shiroshita, Shungo Yamamoto, et al. · Open Forum Infectious Diseases (2025) | TGRS Research Map | TGRS