Effect of intravenous lidocaine introduction on neuromuscular conduction

The use of lidocaine in a regimen of multimodal anesthesia to reduce doses of anesthetics compared to classical anesthesia is a promising direction in modern anesthesiology. The widespread use of local anesthetics in anesthesiological practice has made it possible to identify their significant effect on the neuromuscular profile. However, the available research on combinations of these drugs with muscle relaxants is very contradictory. Objective . To study the effects of preoperative intravenous lidocaine on neuromuscular conduction. Materials and methods . In order to assess the effect of lidocaine on neuromuscular conduction, 60 patients (ASA I–II) were examined, who underwent laparoscopic cholecystectomy for chronic calculous cholecystitis. Two groups were formed: patients using lidocaine at a dose of 2 mg·kg-1 (30 people, the first group), and patients who used saline (30 people, the second group). Neuromuscular conduction was assessed using the acceleromyography method (monitor TOF-Watch SX). Results . The rate of recovery of neuromuscular conduction was within 47 and 48 minutes in groups 1 and 2, respectively (p=0.92). Conclusion . As a result of the study, it was found that lidocaine did not statistically have a significant effect on neuromuscular transmission.