Sustained Clinical Remission of BRAF V600E-Mutated Langerhans Cell Histiocytosis With Multiorgan Involvement in an Infant Treated With Dabrafenib
Multisystem LCH is a rare and potentially life-threatening disease that can mimic various neonatal conditions. A high index of suspicion is necessary for diagnosis. Timely initiation of targeted therapy may prevent irreversible organ damage.
Authors
- Jean Donadieu (ORCID: https://orcid.org/0000-0002-4485-146X)
- Susanne Holzhauer (ORCID: https://orcid.org/0000-0003-2118-6230)
- Franziska Cuntz (ORCID: https://orcid.org/0009-0001-6392-2139)
Institutions
- Université Paris-Saclay (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Journal of Pediatric Hematology/Oncology
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1097/mph.0000000000003014
- Primary Topic
- Histiocytic Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00