Glucose protects cultured retinal cells from oxidative injury via the pentose phosphate pathway
Glucose prevented oxidative stress to retinal cells via the PPP. Neurons were not subjected to glucose-induced protection except when glial cells were present, implying the passage of a transmissible mediator or other protective action between the two cell types.
Authors
- Glyn Chidlow (ORCID: https://orcid.org/0000-0001-7371-0239)
- John P. M. Wood (ORCID: https://orcid.org/0000-0001-8233-7640)
- Robert J. Casson (ORCID: https://orcid.org/0000-0003-2822-4076)
Institutions
- Royal Adelaide Hospital (AU)
- South Australian Health and Medical Research Institute (AU)
Publication Details
- Journal
- Free Radical Biology and Medicine
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1016/j.freeradbiomed.2025.03.006
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00