[Quercetin mitigates HIV-1 gp120-induced rat astrocyte neurotoxicity <i>via</i> promoting G3BP1 disassembly in stress granules].
Quercetin mitigates HIV-1 gp120-induced astrocyte neurotoxicity and cognitive function impairment by inhibiting oxidative stress, enhancing expressions of SG depolymerization-related proteins, and promoting SG disassembly, suggesting the value of quercetin as a potential therapeutic agent for neuroprotection in HIV-associated neurocognitive disorders.
Authors
- Hong Cao (ORCID: https://orcid.org/0000-0002-8574-6420)
- Xuefeng Gao (ORCID: https://orcid.org/0000-0002-1174-0536)
- Jinhu Zou (ORCID: https://orcid.org/0000-0002-4861-9414)
- Pengwei Huang
- Jie Chen (ORCID: https://orcid.org/0000-0002-5183-4852)
Institutions
- Southern Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-02-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.02.11
- Primary Topic
- Tryptophan and brain disorders
- Type
- article