A Challenging Case of Inferior Vena Cava Compression in an Adult Polycystic Kidney Disease Patient. A Case Report

Adult polycystic kidney disease (ADPKD) is a multi-system genetic disorder characterized by the development and progressive enlargement of fluid-filled cysts in both kidneys, along with other organs. As one of the main causes of kidney failure, ADPKD can progress to end-stage renal disease (ESRD), with over 50% of affected individuals progressing to ESRD by age 50. The symptoms in ADPKD are variable, with some patients experiencing nonspecific signs, while others present with symptoms related to the mass effect of enlarged kidneys on surrounding structures. This case report highlights an unusual presentation of ADPKD in a patient who developed symptoms of inferior vena cava (IVC) compression. Remarkably, these symptoms improved after bilateral nephrectomies, suggesting that bilateral nephrectomy would provide help in these situations.