[LINC00837/miR-671-5p/SERPINE2 functional axis promotes pathological processes of fibroblast-like synovial cells in rheumatoid arthritis].

RA-FLS have a LINC00837/miR-671-5p/SERPINE2 functional axis, which regulates cell proliferation, migration and secretion of inflammatory factors, and interventions targeting LINC00837 may provide a potential strategy to regulate the pathological processes in RA-FLS.

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Publication Details

Journal
PubMed
Published
2025-02-20
DOI
https://doi.org/10.12122/j.issn.1673-4254.2025.02.18
Primary Topic
Cancer-related molecular mechanisms research
Type
article
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article

[LINC00837/miR-671-5p/SERPINE2 functional axis promotes pathological processes of fibroblast-like synovial cells in rheumatoid arthritis].

Mengna Wang, Zhifei Cao, Yuan Wang, Yue Sun et al.
PubMed
Cancer-related molecular mechanisms research
article

[LINC00837/miR-671-5p/SERPINE2 functional axis promotes pathological processes of fibroblast-like synovial cells in rheumatoid arthritis].

Mengna Wang, Zhifei Cao, Yuan Wang, Yue Sun, Feifei Liu
article en

Abstract

RA-FLS have a LINC00837/miR-671-5p/SERPINE2 functional axis, which regulates cell proliferation, migration and secretion of inflammatory factors, and interventions targeting LINC00837 may provide a potential strategy to regulate the pathological processes in RA-FLS.

PubMedVol. 45(2)
Anhui University of Traditional Chinese Medicine (CN)
Cancer-related molecular mechanisms research
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