Green synthesis of Chitosan nanoparticles (CHNPs) using Azardiracta indica leaf extract: potential to antibacterial and antibiofilm properties: in-vitro analysis

The present study investigated the Chitosan nanoparticles (CHNPs) synthesized from Azardiracta indica leaf against Enterococcus faecalis and Streptococcus mutans for antibacterial and antibiofilm properties. O. sanctum leaf extracts synthesized chitosan nanoparticles sustainably. Synthesized chitosan nanoparticles were characterized by UV-visible, transmission electron microscopy, FTIR, and X-ray diffraction. Then, chitosan nanoparticles (CHNPs) were tested for antibacterial and antibiofilm activity against dental caries-causing organisms such S. mutans and E. faecalis(Deepika et al. 2022). The characterization of the nanoparticles (NPs) indicated that the biosynthesized NPs were spherical in shape.