Lipoid necrobiosis (clinical case)

Lipoid necrobiosis, commonly known as necrobiosis lipoidica, shares similarities with skin dyslipidosis, diabetic lipoid necrobiosis, and Oppenheim-Urbach disease. It is a chronic skin condition linked to diverse metabolic impairments, emerging in the context of disrupted carbohydrate metabolism and microcirculation, particularly in cases of type 2 diabetes mellitus. Timely and accurate diagnosis, along with the elimination of causative factors, are crucial for determining the appropriate treatment regimen.Additionally, associations have been observed with thyroid autoimmune diseases, Crohn's disease, ulcerative colitis, sarcoidosis, and vitiligo, which may be attributed to phenotypic and functional abnormalities in cellular immunity.