Multi-omics study on autophagic dysfunction molecular network in the pathogenesis of rheumatoid arthritis
We identified that autophagy-related genes BCL2L1 and RAF1 may be associated with RA risk, providing strong evidence from multi-omics data. This study identifies autophagy genes related to RA, potentially offering new insights into the pathogenesis of RA.
Authors
- Yajuan Guo (ORCID: https://orcid.org/0000-0002-6344-5248)
- Youji Jia
- Yichen Zhao
- Xiaobing Xi (ORCID: https://orcid.org/0000-0003-0897-3352)
- Honghong Ma
- Wei Yan (ORCID: https://orcid.org/0000-0003-0619-5876)
- Ping Jiang (ORCID: https://orcid.org/0009-0005-8347-7422)
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1186/s12967-025-06288-7
- Citations
- 6
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 8.13