Hydrogen alleviates myocardial infarction by impeding apoptosis via ROS-mediated mitochondrial endogenous pathway
Overall, hydrogen inhalation reduces myocardial infarct size, improves mitochondrial dysfunction, and modulates the levels of apoptosis-related substances. Importantly, Hydrogen reduces acute myocardial infarction damage by downregulating ROS and upregulating antioxidant proteins.
Authors
- Xiaojian Hong
- Chaoqun Nie (ORCID: https://orcid.org/0000-0003-2405-1913)
- Rentong Zou
- Mengshu Yu
- Bin Wang (ORCID: https://orcid.org/0000-0002-8582-1865)
- Jiawen Zhang (ORCID: https://orcid.org/0000-0003-0489-776X)
- Shuang Pan (ORCID: https://orcid.org/0000-0001-8434-0210)
- Xinrui Yang (ORCID: https://orcid.org/0000-0002-3506-4106)
- Zhuoqun Zhang (ORCID: https://orcid.org/0000-0003-1573-0922)
- Wei Yang (ORCID: https://orcid.org/0000-0001-8687-6473)
- Bowei Fan
Institutions
- Qingdao University (CN)
- Harbin Medical University (CN)
- Yuhuangding Hospital (CN)
- Fourth Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Free Radical Research
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1080/10715762.2025.2474014
- Citations
- 4
- Primary Topic
- Hydrogen's biological and therapeutic effects
- Type
- article
- Field-Weighted Citation Impact
- 8.03