A Pragmatic Approach to Monitor for Adrenal Axis Recovery After a Failed Short Synacthen Test
An early morning cortisol ≤126 nmol/L is common in those followed for adrenal axis recovery and is an accurate indicator of non-recovery. Baseline cortisol measurements are therefore a simple way of screening for adrenal axis recovery. Those with a cortisol of >126 nmol/L should go on to have an SST. Using this approach could considerably reduce the need for follow up SSTs in this patient cohort.
Authors
- Daniel Flanagan (ORCID: https://orcid.org/0000-0002-1833-1276)
- Matthew Rowe (ORCID: https://orcid.org/0000-0002-6931-8805)
- Jinny Jeffery (ORCID: https://orcid.org/0000-0002-7380-7476)
- Andrew McGovern (ORCID: https://orcid.org/0000-0002-6833-9399)
- Nishchil Patel
- Anes Harid
Institutions
- Derriford Hospital (GB)
- University Hospitals Plymouth NHS Trust (GB)
- University of Plymouth (GB)
Publication Details
- Journal
- Endocrine Practice
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1016/j.eprac.2025.02.019
- Primary Topic
- Adrenal Hormones and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- NIHR Imperial Biomedical Research Centre
- NIHR Leicester Biomedical Research Centre