Amentoflavone protects against cisplatin-induced acute kidney injury by modulating Nrf2-mediated oxidative stress and ferroptosis and partially by activating Nrf2-dependent PANoptosis
Amentoflavone has a protective effect on cisplatin-induced acute kidney injury via a mechanism related to the Nrf2-dependent antioxidant pathway and the regulation of ferroptosis and PANoptosis.
Authors
- Jianqiang Hu (ORCID: https://orcid.org/0000-0001-7706-4377)
- Yanmin Zhang (ORCID: https://orcid.org/0000-0001-7307-9408)
- Xinxin Ci (ORCID: https://orcid.org/0000-0003-2207-6869)
- Yan Zhang (ORCID: https://orcid.org/0000-0003-2219-5550)
Institutions
- Jilin University (CN)
- First Hospital of Jilin University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-05
- DOI
- https://doi.org/10.3389/fphar.2025.1508047
- Citations
- 7
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 10.63
Funders
- Natural Science Foundation of Jilin Province