Bioinformatics analysis of electroacupuncture treatment for ischemic stroke: exploring transcriptional regulatory mechanisms mediated by super-enhancers
Overall, our findings provide novel insights into the molecular mechanisms by which acupuncture may treat ischemic stroke, identifying key SE target genes and transcriptional circuits as promising targets for future therapeutic strategies. Further research is warranted to validate these findings in clinical settings and explore the translational potential of acupuncture in ischemic stroke treatment.
Authors
- Chunzhi Tang (ORCID: https://orcid.org/0000-0003-3127-578X)
- Qizhang Wang (ORCID: https://orcid.org/0000-0001-9529-976X)
- Chunxiao Wu (ORCID: https://orcid.org/0000-0002-8637-5545)
- C Deng
- Zhirui Xu
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Shenzhen Pingle Orthopedic Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-03-05
- DOI
- https://doi.org/10.3389/fnins.2025.1522466
- Citations
- 1
- Primary Topic
- Bioinformatics and Genomic Networks
- Type
- article
- Field-Weighted Citation Impact
- 0.81