Facial Porokeratosis – An Uncommon Presentation of an Uncommon Disease

Porokeratosis is an uncommon keratinization disorder characterized by keratotic papules or annular plaques with elevated borders. It has distinctive histological findings. Porokeratosis with exclusive facial lesions is seldom reported. A 25-year-old unmarried female presented with multiple, asymptomatic, brownish plaques ranging in size from 3-6 mm over the face involving both cheeks, the dorsum of the nose, and the forehead. Examination of hair, mucosae, and nails was normal. Systemic examination was unremarkable. Histopathology revealed the presence of coronoid lamella atop a disrupted stratum granulosum and dyskeratotic keratinocytes. These features confirmed the diagnosis of porokeratosis. She was prescribed topical tazarotene gel for application at night for 6 weeks. The patient returned after 1 month with some improvement, and after that lost to follow-up.

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Publication Details

Journal
Nepal Journal of Dermatology Venereology & Leprology
Published
2025-03-04
DOI
https://doi.org/10.3126/njdvl.v23i1.69586
Primary Topic
Genetic and rare skin diseases.
Type
article
Field-Weighted Citation Impact
0.00
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article

Facial Porokeratosis – An Uncommon Presentation of an Uncommon Disease

Moin Ahmad Siddiqui
Nepal Journal of Dermatology Venereology & Leprology
Genetic and rare skin diseases.
article

Facial Porokeratosis – An Uncommon Presentation of an Uncommon Disease

Moin Ahmad Siddiqui
article en

Abstract

Porokeratosis is an uncommon keratinization disorder characterized by keratotic papules or annular plaques with elevated borders. It has distinctive histological findings. Porokeratosis with exclusive facial lesions is seldom reported. A 25-year-old unmarried female presented with multiple, asymptomatic, brownish plaques ranging in size from 3-6 mm over the face involving both cheeks, the dorsum of the nose, and the forehead. Examination of hair, mucosae, and nails was normal. Systemic examination was unremarkable. Histopathology revealed the presence of coronoid lamella atop a disrupted stratum granulosum and dyskeratotic keratinocytes. These features confirmed the diagnosis of porokeratosis. She was prescribed topical tazarotene gel for application at night for 6 weeks. The patient returned after 1 month with some improvement, and after that lost to follow-up.

Nepal Journal of Dermatology Venereology & LeprologyVol. 23(1)
Era's Lucknow Medical College and Hospital (IN)
Openalex Percentile: Top 95%
Genetic and rare skin diseases.
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