Motor protein KIF13B orchestrates hepatic metabolism to prevent metabolic dysfunction-associated fatty liver disease
This work establishes a causal relationship between KIF13B deficiency and MAFLD, emphasizing KIF13B as a potential therapeutic target for treating MAFLD.
Authors
- Yu-Hui Wang (ORCID: https://orcid.org/0000-0003-3085-9820)
- Jingdong Wu
- Guolin Miao
- Xunde Xian (ORCID: https://orcid.org/0000-0003-3059-1254)
- Pingping Lai
- Lianxin Zhang (ORCID: https://orcid.org/0000-0002-5076-9518)
- Wenxi Zhang (ORCID: https://orcid.org/0000-0002-8863-4838)
- Jiabao Guo (ORCID: https://orcid.org/0000-0001-8398-2369)
- Yitong Xu
- Ling Zhang (ORCID: https://orcid.org/0000-0001-8371-5252)
- Dongyu Zhao (ORCID: https://orcid.org/0000-0003-3882-0218)
- J Chen
- Zihao Zhou (ORCID: https://orcid.org/0000-0002-3999-3658)
- J.-Z. Chen
- Yufei Han (ORCID: https://orcid.org/0000-0002-4034-6263)
- Yuanwu Ma (ORCID: https://orcid.org/0000-0002-1882-1777)
- Si Mei (ORCID: https://orcid.org/0000-0002-4263-1121)
- Erdan Dong (ORCID: https://orcid.org/0009-0006-8737-5308)
- Weiwei Huang (ORCID: https://orcid.org/0000-0002-9947-4083)
- Chong Zhang (ORCID: https://orcid.org/0000-0001-5072-5219)
- Guanhua Chen (ORCID: https://orcid.org/0000-0002-7727-4662)
- Yanwei Li (ORCID: https://orcid.org/0000-0003-4089-9789)
- Yiran Liu (ORCID: https://orcid.org/0009-0009-4708-1227)
- Yang Zhao (ORCID: https://orcid.org/0000-0003-1393-7567)
- Yinqi Zhao
- Yang Ding (ORCID: https://orcid.org/0000-0003-0836-7790)
Institutions
- Qingdao University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Qingdao Municipal Hospital (CN)
- Institute of Laboratory Animal Science (CN)
- Peking University Third Hospital (CN)
- Center for Life Sciences (CN)
- China Medical University (CN)
Publication Details
- Journal
- Military Medical Research
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1186/s40779-025-00594-3
- Citations
- 8
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 10.83
Funders
- National Natural Science Foundation of China