Adipose-Derived Mesenchymal Stem Cell Exosomes Encapsulating siIL1R2 Facilitate the Repair of DSS-Induced Intestinal Mucosal Injury
IL1R2 and CCR2 are key mediators of inflammation in DSS-induced intestinal injury. Dual inhibition of IL1R2 and CCR2 holds great promise for alleviating inflammatory responses and improving histological presentations in inflammatory bowel disease.
Authors
- Yimin Ge (ORCID: https://orcid.org/0000-0002-5462-3698)
- Wenbin Zhang (ORCID: https://orcid.org/0000-0002-9295-1019)
- Lei Wang (ORCID: https://orcid.org/0000-0001-8975-0489)
- Song Gao (ORCID: https://orcid.org/0000-0002-5821-3207)
- He Huang (ORCID: https://orcid.org/0000-0002-4682-8335)
Institutions
- Xinjiang Medical University (CN)
- Fifth Affiliated Hospital of Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Immunological Investigations
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1080/08820139.2025.2468959
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00