A Single-Center Experience of En Bloc vs. Single Renal Transplantation on Adult Recipients

Background/Objectives: While there are several debates on en bloc renal transplants and pediatric donors regarding the efficacy and concern for renal mass, multiple studies have supported the notion that transplanting pediatric en bloc kidneys produces comparable results in contrast to single kidneys from living or deceased donors. Methods: This case series included a retrospective analysis of a university medical center, primarily focused on comparing the post-operative outcomes between recipients of pediatric and adult en bloc kidneys, which are horseshoe kidneys, from deceased donors and recipients of single adult kidneys from living or deceased donors. Results: This study demonstrated that the post-operative results in recipients of pediatric en bloc kidneys consisting of serum creatinine and estimated glomerular filtration rate (eGFR) values were lower and higher, respectively, and had a comparable improvement in kidney function at post-transplant, 1-week, 1-month, 3-months, and 1-year post-op marks. Conclusions: Our center data and outcomes indicate that en bloc kidney transplantation from pediatric donors yields comparable results to that of single kidney transplantations from living and deceased donors.

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Publication Details

Journal
Transplantology
Published
2025-03-04
DOI
https://doi.org/10.3390/transplantology6010007
Primary Topic
Organ Donation and Transplantation
Type
article
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article

A Single-Center Experience of En Bloc vs. Single Renal Transplantation on Adult Recipients

Yoon-Jung Chang, Obi Ekwenna, S. Levy Simpson, Megan Charette
Transplantology
Organ Donation and Transplantation
article

A Single-Center Experience of En Bloc vs. Single Renal Transplantation on Adult Recipients

Yoon-Jung Chang, Obi Ekwenna, S. Levy Simpson, Megan Charette
article en

Abstract

Background/Objectives: While there are several debates on en bloc renal transplants and pediatric donors regarding the efficacy and concern for renal mass, multiple studies have supported the notion that transplanting pediatric en bloc kidneys produces comparable results in contrast to single kidneys from living or deceased donors. Methods: This case series included a retrospective analysis of a university medical center, primarily focused on comparing the post-operative outcomes between recipients of pediatric and adult en bloc kidneys, which are horseshoe kidneys, from deceased donors and recipients of single adult kidneys from living or deceased donors. Results: This study demonstrated that the post-operative results in recipients of pediatric en bloc kidneys consisting of serum creatinine and estimated glomerular filtration rate (eGFR) values were lower and higher, respectively, and had a comparable improvement in kidney function at post-transplant, 1-week, 1-month, 3-months, and 1-year post-op marks. Conclusions: Our center data and outcomes indicate that en bloc kidney transplantation from pediatric donors yields comparable results to that of single kidney transplantations from living and deceased donors.

TransplantologyVol. 6(1)
University of Toledo Medical Center (US), University of Toledo (US)
Openalex Percentile: Top 94%
Organ Donation and Transplantation
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A Single-Center Experience of En Bloc vs. Single Renal Transplantation on Adult Recipients — Yoon-Jung Chang, Obi Ekwenna, et al. · Transplantology (2025) | TGRS Research Map | TGRS