Comparison and Optimization of DNA Extraction Methods for Human DNA from Dried Blood Spot Samples
We identified an easy and cost-effective optimized DNA extraction method using Chelex from DBSs, with an elution volume of 50 µL and 1 × 6 mm DBS punch, which is particularly advantageous for research in low-resource settings and large populations, such as neonatal screening programs.
Authors
- Piet Cools (ORCID: https://orcid.org/0000-0003-2980-5307)
- Eline Meyers (ORCID: https://orcid.org/0000-0002-3549-9548)
- Natalja Van Biesen
Institutions
- Ghent University (BE)
Publication Details
- Journal
- Pediatric Reports
- Published
- 2025-03-04
- DOI
- https://doi.org/10.3390/pediatric17020030
- Citations
- 8
- Primary Topic
- Biosimilars and Bioanalytical Methods
- Type
- article
- Field-Weighted Citation Impact
- 6.38
Funders
- Fonds Wetenschappelijk Onderzoek