Are Glucocorticoids Truly Effective in Improving the Clinical Prognosis of HSV-1 Encephalitis?

Despite the hormone group not obtaining the anticipated positive outcomes, potentially due to the relatively limited sample size in this study, previous case series reports have indicated that glucocorticoids, when used as an adjunct to acyclovir therapy, may enhance patient outcomes. Consequently, further extensive clinical studies involving multiple centers and larger sample sizes are warranted to investigate this matter further.

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Publication Details

Journal
Infection and Drug Resistance
Published
2025-03-01
DOI
https://doi.org/10.2147/idr.s501628
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Are Glucocorticoids Truly Effective in Improving the Clinical Prognosis of HSV-1 Encephalitis?

Zhaohui Lai, Wei Sun, Xianghong Liu, Shuhua Xie
Infection and Drug Resistance
Herpesvirus Infections and Treatments
article

Are Glucocorticoids Truly Effective in Improving the Clinical Prognosis of HSV-1 Encephalitis?

Zhaohui Lai, Wei Sun, Xianghong Liu, Shuhua Xie
article en

Abstract

Despite the hormone group not obtaining the anticipated positive outcomes, potentially due to the relatively limited sample size in this study, previous case series reports have indicated that glucocorticoids, when used as an adjunct to acyclovir therapy, may enhance patient outcomes. Consequently, further extensive clinical studies involving multiple centers and larger sample sizes are warranted to investigate this matter further.

Infection and Drug ResistanceVol. Volume 18
Ganzhou People's Hospital (CN)
Zero hunger
Openalex Percentile: Top 94%
Herpesvirus Infections and Treatments
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