Guy A. Rouleau: Genetic foundations of neurological disease – From risk variants to pathogenic mechanisms

In this engaging Genomic Press Interview, Dr. Guy A. Rouleau, OC, OQ, FRCPC, FRSC, FAAN, opens up about his remarkable journey from a young boy conducting chemistry experiments in his basement to becoming Director of The Neuro (Montreal Neurological Institute-Hospital) and Chair of McGill University's Department of Neurology and Neurosurgery. A world-renowned clinician and neurogenetics researcher, Dr. Rouleau has dedicated 35 years to uncovering the genetic foundations of devastating neurological conditions, identifying dozens of disease-causing genes in ALS, hereditary neuropathies, epilepsy, schizophrenia, and autism. His scientific impact is reflected in nearly 1,000 peer-reviewed publications cited over 110,000 times, but his vision for transforming research methodology may be his most lasting legacy. As co-founder of the Tanenbaum Open Science Institute and First Vice-President of the World Federation of Neurology, he is pioneering a revolution in scientific collaboration by establishing The Neuro as the world's first academic institution fully committed to open science principles. Through personal anecdotes and professional insights, Dr. Rouleau shares his passion for sailing, commitment to mentoring the next generation, and unwavering belief that open, collaborative science will accelerate discoveries to benefit patients worldwide.