Altered Production and Cellular Levels of Hydrogen Sulfide (H2S) in Placental Trophoblasts from Pregnancies Affected by Pre-Eclampsia
These data provide plausible evidence that downregulation of CBS and CSE, but not 3-MST, expression may be responsible for reduced free H<sub>2</sub>S production and decreased cellular H<sub>2</sub>S levels in pre-eclamptic placentas. Our data provide further evidence that expression of 3-MST in placental trophoblasts is likely gestational age (developmental)-dependent.
Authors
- Danielle B. Cooper (ORCID: https://orcid.org/0000-0002-9616-7555)
- Xinggui Shen (ORCID: https://orcid.org/0000-0002-4002-9671)
- Yang Gu (ORCID: https://orcid.org/0000-0001-7348-1528)
- Wenji Sheng
- Dani Zoorob (ORCID: https://orcid.org/0000-0002-6471-1528)
- Yuping Wang (ORCID: https://orcid.org/0000-0002-8676-7549)
- Jingxia Sun
- Jie Xu (ORCID: https://orcid.org/0009-0004-5330-4398)
- Xiaodan Chu (ORCID: https://orcid.org/0000-0001-6295-6487)
- D. F. V. Lewis
Institutions
- Harbin Medical University (CN)
- Second Affiliated Hospital of Harbin Medical University (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
- Louisiana State University Health Sciences Center Shreveport (US)
Publication Details
- Journal
- Pathophysiology
- Published
- 2025-03-04
- DOI
- https://doi.org/10.3390/pathophysiology32010010
- Citations
- 3
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 6.17