Deubiquitinating Enzymes Regulate Skeletal Muscle Mitochondrial Quality Control and Insulin Sensitivity in Patients With Type 2 Diabetes
Mitochondrial fragmentation bypasses defects in mitophagy to sustain skeletal muscle quality control in patients with T2D.
Authors
- Melissa L. Erickson (ORCID: https://orcid.org/0000-0003-2953-3073)
- Jacob T. Mey (ORCID: https://orcid.org/0000-0001-6826-7762)
- Elizabeth R. M. Zunica (ORCID: https://orcid.org/0000-0002-6850-6054)
- Gangarao Davuluri
- Kathryn P. Belmont (ORCID: https://orcid.org/0000-0003-2658-1459)
- Christopher L. Axelrod (ORCID: https://orcid.org/0000-0002-1444-8557)
- John P. Kirwan (ORCID: https://orcid.org/0000-0001-7321-9917)
- Elizabeth C. Heintz (ORCID: https://orcid.org/0000-0002-7263-1843)
- Hisashi Fujioka (ORCID: https://orcid.org/0000-0001-8511-7141)
- Charles L. Hoppel (ORCID: https://orcid.org/0000-0001-9755-8091)
- Wagner S. Dantas (ORCID: https://orcid.org/0000-0003-4561-4930)
- Analisa L. Taylor (ORCID: https://orcid.org/0000-0002-1553-5732)
- Ciarán E. Fealy
Institutions
- Pennington Biomedical Research Center (US)
- Louisiana State University (US)
- Cleveland Clinic (US)
- Cleveland Clinic Lerner College of Medicine (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1002/jcsm.13763
- Citations
- 5
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- National Institutes of Health
- National Institute of General Medical Sciences
- National Institute of Diabetes and Digestive and Kidney Diseases