Sex differences in the microglial response to stress and chronic alcohol exposure in mice
We analyzed multiple measures of microglial activation, resulting in a comprehensive assessment of microglial changes mediated by sex, stress, and alcohol. These findings highlight the complexity of microglial contributions to the development of AUD and comorbid mood and stress disorders in men and women.
Authors
- Merrilee Thomas (ORCID: https://orcid.org/0000-0002-3430-0912)
- Marina R. Picciotto (ORCID: https://orcid.org/0000-0002-4404-1280)
- Yann S. Mineur (ORCID: https://orcid.org/0000-0002-8030-6776)
- Alexa R. Soares (ORCID: https://orcid.org/0000-0003-1484-4354)
- Vernon Garcia‐Rivas (ORCID: https://orcid.org/0000-0002-3222-0388)
- Xiaoying Zheng (ORCID: https://orcid.org/0000-0003-1966-044X)
- Caroline Fai
Institutions
- Yale University (US)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1186/s13293-025-00701-y
- Citations
- 9
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 7.58
Funders
- National Institutes of Health