Investigation of the mechanism by which FOXJ2 inhibits proliferation, metastasis and cell cycle progression of ovarian cancer cells through the PI3K/AKT signaling pathway
The silencing of FOXJ2 could repress the growth and metastasis potentials and cause the cell cycle G1/S arrest of OC cells in vitro, which was possibly achieved via targeting the PI3K/AKT pathway.
Authors
- Zengrong Tu
- Ruifang Zhai
- Su Min (ORCID: https://orcid.org/0000-0002-0063-5044)
- Rong Huang (ORCID: https://orcid.org/0000-0001-7219-7728)
- R. Duan
- Liyuan Wang (ORCID: https://orcid.org/0000-0003-0681-8842)
- Han He (ORCID: https://orcid.org/0000-0003-1480-1725)
- Ruifan Gao
Institutions
- Shanxi Medical University (CN)
- First People's Hospital of Foshan (CN)
- First Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1186/s40001-025-02270-7
- Citations
- 2
- Primary Topic
- FOXO transcription factor regulation
- Type
- article
- Field-Weighted Citation Impact
- 1.61