Four-Dimensional Visualization of Topological Fixed Points in Pulsatile Cardiovascular Flows

Topological features of time-dependent, three-dimensional (3D) vector flow fields, such as wall shear stress (WSS) fixed points, are considered surrogates of pathological blood flow dynamics in cardiovascular diseases. Fixed-point visualizations are typically constrained to two-dimensional (2D) spaces, yet they aim to display complex spatiotemporal (four-dimensional (4D)) dynamics. There is a need for visualization strategies to reduce occlusion and reliance on animations to allow the detection of holistic flow patterns. Using intracranial aneurysms as a use case, we present the fixed-point carousel, a novel approach to visually depicting the "4D" nature of WSS fixed points via (1) topographic mapping of the 3D aneurysm sac to overcome occlusion while preserving fixed-point distances and sac morphological features; and (2) arranging these into a carousel model to present with temporal dimension holistically. Examples are presented for image-based computational fluid dynamic (CFD) models of intracranial aneurysms, illuminating the intricate and distinct fixed-point trajectories and interactions, a necessary step toward understanding the volumetric flow manifolds that drive them for this and other cardiovascular-and potentially nonbiomedical-fluid dynamics applications.

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Publication Details

Journal
Journal of Biomechanical Engineering
Published
2025-03-04
DOI
https://doi.org/10.1115/1.4068078
Primary Topic
Intracranial Aneurysms: Treatment and Complications
Type
article
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article

Four-Dimensional Visualization of Topological Fixed Points in Pulsatile Cardiovascular Flows

David A. Steinman, Peter Coppin, Thangam Natarajan, Zainab Husain
Journal of Biomechanical Engineering
Intracranial Aneurysms: Treatment and Complications
article

Four-Dimensional Visualization of Topological Fixed Points in Pulsatile Cardiovascular Flows

David A. Steinman, Peter Coppin, Thangam Natarajan, Zainab Husain
article en

Abstract

Topological features of time-dependent, three-dimensional (3D) vector flow fields, such as wall shear stress (WSS) fixed points, are considered surrogates of pathological blood flow dynamics in cardiovascular diseases. Fixed-point visualizations are typically constrained to two-dimensional (2D) spaces, yet they aim to display complex spatiotemporal (four-dimensional (4D)) dynamics. There is a need for visualization strategies to reduce occlusion and reliance on animations to allow the detection of holistic flow patterns. Using intracranial aneurysms as a use case, we present the fixed-point carousel, a novel approach to visually depicting the "4D" nature of WSS fixed points via (1) topographic mapping of the 3D aneurysm sac to overcome occlusion while preserving fixed-point distances and sac morphological features; and (2) arranging these into a carousel model to present with temporal dimension holistically. Examples are presented for image-based computational fluid dynamic (CFD) models of intracranial aneurysms, illuminating the intricate and distinct fixed-point trajectories and interactions, a necessary step toward understanding the volumetric flow manifolds that drive them for this and other cardiovascular-and potentially nonbiomedical-fluid dynamics applications.

Journal of Biomechanical EngineeringVol. 147(5)
Georgia Institute of Technology (US), University of Toronto (CA), Ontario College of Art and Design (CA)
Openalex Percentile: Top 93%
Intracranial Aneurysms: Treatment and Complications
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Four-Dimensional Visualization of Topological Fixed Points in Pulsatile Cardiovascular Flows — David A. Steinman, Peter Coppin, et al. · Journal of Biomechanical Engineering (2025) | TGRS Research Map | TGRS