Chrysin ameliorates dextran sulfate-induced ulcerative colitis in mice by modulating inflammation and gut microbiota
The findings suggest that Chrysin exerts a dual-action therapeutic effect on ulcerative colitis by reducing inflammation and modulating the gut microbiota. These multifaceted impacts highlight Chrysin's potential utility as a novel therapeutic agent in the clinical management of IBD, offering valuable insights into its mechanisms of action and paving the way for future clinical trials.
Authors
- Yang Li (ORCID: https://orcid.org/0000-0001-8123-0876)
- Xin Yao (ORCID: https://orcid.org/0000-0002-7214-2441)
- Huaqiang Li (ORCID: https://orcid.org/0000-0002-6096-3752)
- Xia Liu (ORCID: https://orcid.org/0000-0002-3887-5350)
- Yao Chen (ORCID: https://orcid.org/0000-0002-7120-0902)
- Peng Wang (ORCID: https://orcid.org/0000-0003-0788-6687)
- Daqi Jia
- Chunfang Guo
- Jingyun Mo
Institutions
- Army Medical University (CN)
- Xinqiao Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- International Journal of Colorectal Disease
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1007/s00384-025-04843-8
- Citations
- 6
- Primary Topic
- Flavonoids in Medical Research
- Type
- article
- Field-Weighted Citation Impact
- 8.37
Funders
- Centre Scientifique et Technique du Bâtiment