Electroacupuncture produces analgesic effects via cannabinoid CB1 receptor-mediated GABAergic neuronal inhibition in the rostral ventromedial medulla
The study indicates that the analgesic effect of EA in inflammatory and neuropathic pain is facilitated by CB1 receptor-mediated inhibition of GABA<sup>RVM</sup> neurons.
Authors
- Yuming Wu (ORCID: https://orcid.org/0000-0002-3282-056X)
- Chi Cui (ORCID: https://orcid.org/0000-0002-0657-3163)
- Xiang‐Hong Jing (ORCID: https://orcid.org/0000-0003-0272-1576)
- Kailing Zhang (ORCID: https://orcid.org/0000-0002-3202-4328)
- Ziyu Zhou (ORCID: https://orcid.org/0000-0001-7565-9414)
- J. Mei (ORCID: https://orcid.org/0000-0003-3245-3461)
- Hui‐Lin Pan (ORCID: https://orcid.org/0000-0001-8444-3770)
- Man Li (ORCID: https://orcid.org/0000-0003-4041-0437)
- Yulong Shi
- Qian Xu (ORCID: https://orcid.org/0000-0001-9262-3595)
- He Zhu (ORCID: https://orcid.org/0000-0001-5107-7575)
- Qiang Yao (ORCID: https://orcid.org/0000-0003-0838-4179)
- Jie Lei (ORCID: https://orcid.org/0000-0002-4135-429X)
- Yunqing Rao (ORCID: https://orcid.org/0000-0003-2191-3338)
- Ke-Xing Wan
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Hubei University of Chinese Medicine (CN)
- Central People's Hospital of Zhanjiang (CN)
- China Academy of Chinese Medical Sciences (CN)
- China Association of Acupuncture-Moxibustion (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1186/s13020-025-01083-4
- Citations
- 8
- Primary Topic
- Acupuncture Treatment Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 19.05
Funders
- National Natural Science Foundation of China