Dissecting the causal effects of smoking, alcohol consumption, and related DNA methylation markers on electrocardiographic indices
There is a causal relationship between DrnkWk and QT interval prolongation, and targeting specific DNA methylation sites like cg04605617 mapped to PLA2G2C may provide novel targets for preventing QT interval prolongation.
Authors
- Yongfei Song (ORCID: https://orcid.org/0000-0001-6762-9899)
- Xinhan Li (ORCID: https://orcid.org/0009-0002-6067-4683)
- Xuerui Tan (ORCID: https://orcid.org/0000-0002-4489-9498)
- Zequn Zheng (ORCID: https://orcid.org/0000-0002-5166-2528)
- Tāo Luò (ORCID: https://orcid.org/0000-0002-2929-2233)
Institutions
- Ningbo University (CN)
- Wenzhou Medical University (CN)
- Shantou University (CN)
- Ji Hua Laboratory (CN)
- Ningbo Medical Center Lihuili Hospital (CN)
- First Affiliated Hospital of Shantou University Medical College (CN)
- Hangzhou Medical College (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1186/s13148-025-01851-x
- Citations
- 1
- Primary Topic
- Cardiovascular Disease and Adiposity
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China