Effects of YAP Inhibitors and Activators on the Growth of Leukemia Cells
YAP activators suppressed the growth of leukemia cells through induction of apoptosis. This suggested that YAP might function as a tumor suppressor in leukemia. SBP-3264 and XMU-MP-1 could be novel candidate molecular-targeted drugs for leukemia; however, further investigations are required.
Authors
- Shuji Tohda (ORCID: https://orcid.org/0000-0002-2642-5459)
- Mai Itoh
- HONOKA SEZUTSU
Institutions
- Institute of Science Tokyo (JP)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-03-01
- DOI
- https://doi.org/10.21873/anticanres.17485
- Citations
- 1
- Primary Topic
- Cell death mechanisms and regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.81