Effects of YAP Inhibitors and Activators on the Growth of Leukemia Cells

YAP activators suppressed the growth of leukemia cells through induction of apoptosis. This suggested that YAP might function as a tumor suppressor in leukemia. SBP-3264 and XMU-MP-1 could be novel candidate molecular-targeted drugs for leukemia; however, further investigations are required.

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Publication Details

Journal
Anticancer Research
Published
2025-03-01
DOI
https://doi.org/10.21873/anticanres.17485
Citations
1
Primary Topic
Cell death mechanisms and regulation
Type
article
Field-Weighted Citation Impact
0.81
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article

Effects of YAP Inhibitors and Activators on the Growth of Leukemia Cells

Shuji Tohda, Mai Itoh, HONOKA SEZUTSU
1 citations
Anticancer Research
Cell death mechanisms and regulation
0.81
article

Effects of YAP Inhibitors and Activators on the Growth of Leukemia Cells

Shuji Tohda, Mai Itoh, HONOKA SEZUTSU
article en
1 citations

Abstract

YAP activators suppressed the growth of leukemia cells through induction of apoptosis. This suggested that YAP might function as a tumor suppressor in leukemia. SBP-3264 and XMU-MP-1 could be novel candidate molecular-targeted drugs for leukemia; however, further investigations are required.

Anticancer ResearchVol. 45(3)
Institute of Science Tokyo (JP)
Zero hunger
Openalex Percentile: Top 30%
Cell death mechanisms and regulation
0.81
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Effects of YAP Inhibitors and Activators on the Growth of Leukemia Cells — Shuji Tohda, Mai Itoh, et al. · Anticancer Research (2025) | TGRS Research Map | TGRS