Angiogenin-induced Osteoclastogenesis Mediates Bone Destruction in Oral Squamous Carcinoma

ANG mediates oral cancer-induced bone destruction by promoting osteoclast formation and resorption. These findings suggest that ANG could be a potential therapeutic target for suppressing tumor growth, angiogenesis, and bone destruction in oral cancer therapy.

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Publication Details

Journal
Anticancer Research
Published
2025-03-01
DOI
https://doi.org/10.21873/anticanres.17489
Primary Topic
Bone Metabolism and Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Angiogenin-induced Osteoclastogenesis Mediates Bone Destruction in Oral Squamous Carcinoma

Ken Aoki, Hirohiko Okamura, Soichiro Ibaragi, Jumpei Teramachi et al.
Anticancer Research
Bone Metabolism and Diseases
article

Angiogenin-induced Osteoclastogenesis Mediates Bone Destruction in Oral Squamous Carcinoma

Ken Aoki, Hirohiko Okamura, Soichiro Ibaragi, Jumpei Teramachi, Norie YOSHIOKA, Mika Ikegame, Naito Kurio, Nana Yoshitani
article en

Abstract

ANG mediates oral cancer-induced bone destruction by promoting osteoclast formation and resorption. These findings suggest that ANG could be a potential therapeutic target for suppressing tumor growth, angiogenesis, and bone destruction in oral cancer therapy.

Anticancer ResearchVol. 45(3)
Okayama University (JP), Tokushima University (JP)
Openalex Percentile: Top 96%
Bone Metabolism and Diseases
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