Schizotypy, Psychosis Proneness, and the Polygenic Risk for Schizophrenia and Resilience
These results further support the idea of a (partially) shared genetic basis of schizophrenia and nonclinical, predominantly positive expressions of the psychosis spectrum but also indicate relevant distinctions between the 2, possibly related to other modulating factors or general (transdiagnostic) psychopathological risk. In line with previous findings, effects seem to be more robust for state- than trait-level markers, but these may also be influencing each other.
Authors
- Tina Meller (ORCID: https://orcid.org/0000-0002-0239-6585)
- Carlo Maj (ORCID: https://orcid.org/0000-0002-9559-1725)
- Catarina Lundberg (ORCID: https://orcid.org/0000-0003-2342-7317)
- Andreas J. Forstner (ORCID: https://orcid.org/0000-0002-1876-6368)
- Igor Nenadić (ORCID: https://orcid.org/0000-0002-0749-7473)
- Markus M. Nöthen (ORCID: https://orcid.org/0000-0002-8770-2464)
- Per Hoffmann
Institutions
- University of Bonn (DE)
- Philipps University of Marburg (DE)
- Forschungszentrum Jülich (DE)
- University Hospital Bonn (DE)
- Center for Human Genetics (US)
- Loewe Center for Synthetic Microbiology (DE)
Publication Details
- Journal
- Schizophrenia Bulletin
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1093/schbul/sbae161
- Citations
- 4
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.88
Funders
- Deutsche Forschungsgemeinschaft
- Uniklinikum Giessen und Marburg