‘Unveiling the hidden threat: Delayed presentation of congenital syphilis’

Maternal and congenital syphilis are a major public health problem worldwide. The World Health Organization and Centre for Disease Control both recommend routine screening of pregnant females for syphilis. Despite guidelines in place, maternal syphilis often remains undiagnosed and untreated and there is currently a surge in cases of congenital syphilis. We present a case of a 3-month-old male illustrating a delayed diagnosis of congenital syphilis despite characteristic skin lesions, hepatosplenomegaly, haemolytic anaemia, failure to thrive and history of untreated syphilis in the mother. This case highlights the need to strengthen existing guidelines for intensive screening and early treatment for maternal syphilis. It also underscores the importance of increased awareness amongst paediatricians and dermatologists regarding overlapping clinical features of congenital syphilis.

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Publication Details

Journal
Tropical Doctor
Published
2025-03-04
DOI
https://doi.org/10.1177/00494755251325318
Primary Topic
Syphilis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

‘Unveiling the hidden threat: Delayed presentation of congenital syphilis’

Amit Shukla, Anamika Gupta, Namita Mishra
Tropical Doctor
Syphilis Diagnosis and Treatment
article

‘Unveiling the hidden threat: Delayed presentation of congenital syphilis’

Amit Shukla, Anamika Gupta, Namita Mishra
article en

Abstract

Maternal and congenital syphilis are a major public health problem worldwide. The World Health Organization and Centre for Disease Control both recommend routine screening of pregnant females for syphilis. Despite guidelines in place, maternal syphilis often remains undiagnosed and untreated and there is currently a surge in cases of congenital syphilis. We present a case of a 3-month-old male illustrating a delayed diagnosis of congenital syphilis despite characteristic skin lesions, hepatosplenomegaly, haemolytic anaemia, failure to thrive and history of untreated syphilis in the mother. This case highlights the need to strengthen existing guidelines for intensive screening and early treatment for maternal syphilis. It also underscores the importance of increased awareness amongst paediatricians and dermatologists regarding overlapping clinical features of congenital syphilis.

Tropical DoctorVol. 55(2)
All India Institute of Medical Sciences Raipur (IN), All India Institute of Medical Sciences Bhopal (IN), All India Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 95%
Syphilis Diagnosis and Treatment
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‘Unveiling the hidden threat: Delayed presentation of congenital syphilis’ — Amit Shukla, Anamika Gupta, et al. · Tropical Doctor (2025) | TGRS Research Map | TGRS