How many doses and what type of antibiotic should be used as systemic antibiotic prophylaxis in primary hip and knee arthroplasty? A register-based study on 301,204 primary total and hemi- hip and total knee arthroplasties in Norway 2005–2023
4 doses of SAP did not reduce the risk of PJI compared with 1 to 3 doses in primary arthroplasty as measured against PJI. Cefazolin, the 1st-generation cephalosporin with the longest half-life, showed the lowest risk of PJI.
Authors
- Geir Hallan (ORCID: https://orcid.org/0000-0002-8202-3462)
- Håvard Dale
- Christian Thomas Pollmann (ORCID: https://orcid.org/0000-0002-3869-0129)
- Jan‐Erik Gjertsen (ORCID: https://orcid.org/0000-0002-8490-268X)
- Trond Bruun (ORCID: https://orcid.org/0000-0002-7441-8413)
- Marianne Bollestad Tjørhom (ORCID: https://orcid.org/0000-0002-8612-7728)
- Lars B. Engesæter (ORCID: https://orcid.org/0000-0003-3126-3164)
- Ove Furnes (ORCID: https://orcid.org/0000-0001-8223-2515)
- Tesfaye Hordofa Leta (ORCID: https://orcid.org/0000-0002-9596-507X)
- Tina S Wik (ORCID: https://orcid.org/0000-0001-7317-5475)
- Olav Lutro (ORCID: https://orcid.org/0000-0003-3312-3712)
- Stein Håkon Låstad Lygre (ORCID: https://orcid.org/0000-0001-9146-4510)
- Marianne Westberg
Institutions
- Oslo University Hospital (NO)
- Stavanger University Hospital (NO)
- Akershus University Hospital (NO)
- Haukeland University Hospital (NO)
- VID Specialized University (NO)
- St Olav's University Hospital (NO)
- University of Bergen (NO)
Publication Details
- Journal
- Acta Orthopaedica
- Published
- 2025-03-04
- DOI
- https://doi.org/10.2340/17453674.2025.43003
- Citations
- 3
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.02