The circular RNA circbabo(5,6,7,8S) regulates lipid metabolism and neuronal integrity via TGF-β/ROS/JNK/SREBP signaling axis in Drosophila
Our study demonstrates the physiological role of the protein-coding circRNA circbabo(5,6,7,8S) in regulating lipid metabolism and neuronal integrity.
Authors
- Rui Zhou (ORCID: https://orcid.org/0000-0002-1818-7710)
- Jian‐Liang Li
- Aimin Xu (ORCID: https://orcid.org/0000-0002-0668-033X)
- J. Min (ORCID: https://orcid.org/0009-0009-8275-8168)
- Weihong Liang (ORCID: https://orcid.org/0000-0002-1143-6681)
- Jennifer W. Li
- Junfang Lyu
- Xingyu Xu (ORCID: https://orcid.org/0000-0002-7056-8748)
- Xuemei Zhang (ORCID: https://orcid.org/0000-0002-4979-6965)
- Wei Liu (ORCID: https://orcid.org/0000-0001-8430-0497)
- Jie Sheng (ORCID: https://orcid.org/0000-0001-8196-8600)
- Bei Zhang
Institutions
- Johns Hopkins University (US)
- Xuzhou Medical College (CN)
- Brown University (US)
- National Institute of Environmental Health Sciences (US)
- Johns Hopkins All Children's Hospital (US)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-03-05
- DOI
- https://doi.org/10.1186/s12915-025-02175-1
- Citations
- 6
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.84
Funders
- National Natural Science Foundation of China
- National Institutes of Health