Differential Association of Schizotypy Dimensions With Brain Structural Connectivity and Moderation by Schizophrenia Polygenic Risk
Our results support a neurobiological continuum model of structural connectivity across psychosis proneness, emphasizing differential association with different schizotypy facets. Genetic schizophrenia risk, however, appears to impact only some of these associations, highlighting the need for further studies to understand the contribution of other genetic and/or environmental factors.
Authors
- Tina Meller (ORCID: https://orcid.org/0000-0002-0239-6585)
- Jonas Hoffmann (ORCID: https://orcid.org/0000-0003-1150-7213)
- Per Hoffmann (ORCID: https://orcid.org/0000-0002-6573-983X)
- Carlo Maj (ORCID: https://orcid.org/0000-0002-9559-1725)
- Andreas J. Forstner (ORCID: https://orcid.org/0000-0002-1876-6368)
- Igor Nenadić (ORCID: https://orcid.org/0000-0002-0749-7473)
- Markus M. Nöthen (ORCID: https://orcid.org/0000-0002-8770-2464)
Institutions
- University of Bonn (DE)
- Philipps University of Marburg (DE)
- Forschungszentrum Jülich (DE)
- University Hospital Bonn (DE)
- Center for Human Genetics (US)
- Loewe Center for Synthetic Microbiology (DE)
Publication Details
- Journal
- Schizophrenia Bulletin
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1093/schbul/sbae160
- Citations
- 1
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.36