Esketamine Regulates Mitophagy through ULK1/FUNDC1 Signaling Pathway to Improve LPS-induced Acute Respiratory Distress Syndrome
Collectively, this study revealed the protective role of esketamine against lung injury, inflammation, oxidative stress, and apoptosis in mice with ARDS and revealed the reaction mechanism related to mitophagy.
Authors
- Ping Pei
- Yiqi Weng (ORCID: https://orcid.org/0000-0001-8878-1371)
- Yingli Cao
- Weihua Liu (ORCID: https://orcid.org/0009-0009-5593-9545)
- Mei Ding (ORCID: https://orcid.org/0000-0001-5765-3799)
- Wenli Yu (ORCID: https://orcid.org/0000-0003-2790-9997)
Institutions
- Nankai University (CN)
- Tianjin First Center Hospital (CN)
- Tianjin Fourth Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Current Pharmaceutical Design
- Published
- 2025-03-04
- DOI
- https://doi.org/10.2174/0113816128361112250221065359
- Citations
- 2
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.68