Model-informed drug development of novel ROCK2 inhibitor TDI01: population pharmacokinetic study and simulation
The established model and simulation provide a useful approach to maximize the clinical medication safety and therapeutic efficacy of TDI01.
Authors
- Xiwei Ji
- Yimin Cui (ORCID: https://orcid.org/0000-0002-4186-1005)
Institutions
- Peking University (CN)
- Peking University First Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-04
- DOI
- https://doi.org/10.3389/fphar.2025.1477607
- Citations
- 1
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Key Research and Development Program of China