Evaluation of the Effects of Xylopia aethiopica and Tetrapleura tetraptera on Selected Metabolic Parameters in Wistar Rats

Background: The postpartum period involves significant physiological changes requiring optimal nutrition and hydration. In African communities, Xylopia aethiopica and Tetrapleura tetraptera traditionally support maternal recovery. Despite their widespread use, scientific validation of their effects on food intake, water consumption, and weight regulation remains limited. This study assessed the effects of Xylopia aethiopica and Tetrapleura tetraptera on food intake, water intake, and weight changes in Wistar rats. Methods: Twenty-four female Wistar rats (87–103 g) were randomised into four groups (n = 6): control (standard rat chow), X. aethiopica (100 mg/kg extract), T. tetraptera (100 mg/kg extract), and a combined group (50 mg/kg of each extract). Food and water intake were recorded daily for 14 days, while body weights were measured at baseline and Day 14. Data were analysed using one-way ANOVA and Tukey’s post hoc tests (p<0.05). Results: All treatment groups demonstrated significantly higher food and water intake than controls, with the X. aethiopica group having the highest intake (food: 95.3 g/day; water: 91.57 ml/day). Weight changes were minimal and statistically insignificant. Conclusion: Xylopia aethiopica and Tetrapleura tetraptera significantly enhance food and water intake without causing excessive weight gain.