Colorectal Cancer Arising in a Colon Interposition After Esophageal Reconstruction: The Medical Oncology Perspective

Severe esophageal disease can be remedied with colonic interposition, a surgical procedure in which the resected esophagus is replaced by a segment of colon. The development of adenocarcinoma in the colon conduit is a rare but growing long-term complication of this procedure. Here, we present a case of colorectal cancer that developed decades after colonic interposition for childhood esophageal injury due to caustic ingestion. We highlight the challenges inherent in evaluation, treatment, surveillance, and survivorship for this unfortunate complication and describe our institution's successful approach to this complex case.