Acute effects of Δ9-tetrahydrocannabinol on computational measures of neurocognitive processes are related to recent cannabis use among adolescents and young adults
Results add to our understanding of the acute neurocognitive effects of THC. Slower cognitive efficiency after THC was highly heterogeneous, and was related to both recent cannabis use and subjective drug effects. These findings support the notion that acute effects of cannabis on cognitive efficiency (GNG drift rate) are reduced by individuals' tolerance to cannabis.
Authors
- Natania A. Crane (ORCID: https://orcid.org/0000-0003-0487-1404)
- Alex Weigard
- Katie J. Paige (ORCID: https://orcid.org/0000-0002-3229-1960)
- Heide Klumpp (ORCID: https://orcid.org/0000-0003-3406-1373)
- Harriet de Wit (ORCID: https://orcid.org/0000-0002-7211-8994)
- K. Luan Phan
- Olusola Ajilore (ORCID: https://orcid.org/0000-0003-0737-0437)
Institutions
- University of Michigan (US)
- University of Illinois Chicago (US)
- University of Chicago (US)
- The Ohio State University (US)
Publication Details
- Journal
- Frontiers in Adolescent Medicine
- Published
- 2025-03-04
- DOI
- https://doi.org/10.3389/fradm.2025.1541068
- Citations
- 1
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Institutes of Health
- National Institute on Alcohol Abuse and Alcoholism
- National Institute on Drug Abuse