A Rare Case of Hyperkalemia Following Magnesium Sulfate Therapy in a Pregnant Patient With Preeclampsia

A 21-year-old woman at 36 weeks’ gestation presented with preeclampsia and received intravenous magnesium sulfate for seizure prevention. Her magnesium level peaked at 7.4 mg/dL on day 2. By day 4, her potassium level peaked at 6.3 mmol/L, with peaked T waves on electrocardiogram. She was treated with potassium-lowering therapy, and her kidney function remained normal, though aldosterone levels were slightly low. Given the rise in her potassium level following hypermagnesemia and its normalization after her magnesium level decreased, hyperkalemia was attributed to an elevated magnesium level. This is the fourth reported case of hyperkalemia following magnesium administration.

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Publication Details

Journal
Annals of Internal Medicine Clinical Cases
Published
2025-03-01
DOI
https://doi.org/10.7326/aimcc.2024.1013
Primary Topic
Magnesium in Health and Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

A Rare Case of Hyperkalemia Following Magnesium Sulfate Therapy in a Pregnant Patient With Preeclampsia

Mohamad Hosam Horani, Rishad Ahmed, Mahad Alam, Talal Alomar et al.
Annals of Internal Medicine Clinical Cases
Magnesium in Health and Disease
article

A Rare Case of Hyperkalemia Following Magnesium Sulfate Therapy in a Pregnant Patient With Preeclampsia

Mohamad Hosam Horani, Rishad Ahmed, Mahad Alam, Talal Alomar, Anas Kartoumah
article en

Abstract

A 21-year-old woman at 36 weeks’ gestation presented with preeclampsia and received intravenous magnesium sulfate for seizure prevention. Her magnesium level peaked at 7.4 mg/dL on day 2. By day 4, her potassium level peaked at 6.3 mmol/L, with peaked T waves on electrocardiogram. She was treated with potassium-lowering therapy, and her kidney function remained normal, though aldosterone levels were slightly low. Given the rise in her potassium level following hypermagnesemia and its normalization after her magnesium level decreased, hyperkalemia was attributed to an elevated magnesium level. This is the fourth reported case of hyperkalemia following magnesium administration.

Annals of Internal Medicine Clinical CasesVol. 4(3)
Creighton University (US), Arizona State University (US), Edward Via College of Osteopathic Medicine (US)
Openalex Percentile: Top 95%
Magnesium in Health and Disease
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A Rare Case of Hyperkalemia Following Magnesium Sulfate Therapy in a Pregnant Patient With Preeclampsia — Mohamad Hosam Horani, Rishad Ahmed, et al. · Annals of Internal Medicine Clinical Cases (2025) | TGRS Research Map | TGRS