Exploring safe practice when handling cytotoxic drugs: findings from survey of UK cancer nurses

Background Cytotoxic drugs, including chemotherapy, potentially pose significant risks to cancer nurses. Therefore, it is important to take measures to protect them from the health effects associated with these drugs. Aim To determine UK cancer nurses’ perceptions and experiences regarding potential exposure to cytotoxic drugs, including their knowledge of hazards, use of personal protective equipment (PPE) and closed system transfer devices (CSTDs), and perceived health effects. Method A cross-sectional survey was conducted across the UK, facilitated through the UK Oncology Nursing Society. Descriptive analyses were employed. Results The survey revealed that the PPE predominantly used by respondents when administering cytotoxic drugs were plastic aprons (97%, n=723/747) and either gloves labelled for use with chemotherapy (62%, n=466/747) or other gloves (53%, n=393/747). Around 70% (n=521/747) of respondents had used CSTDs during administration. Perceived health effects associated with handling cytotoxic drugs were reported by 161 respondents. Conclusion This study indicates that most cancer nurses have a high level of knowledge of the hazards of cytotoxic drugs, and that plastic aprons and gloves are the primary protection used against occupational exposure. However, there appear to be variation in their use of CSTDs. Many cancer nurses perceive their health to be compromised due to the handling of cytotoxic drugs. It is recommended that all cancer treatment settings across the UK should implement CSTDs.

Authors

Institutions

Publication Details

Journal
Cancer Nursing Practice
Published
2025-03-04
DOI
https://doi.org/10.7748/cnp.2025.e1878
Citations
3
Primary Topic
Safe Handling of Antineoplastic Drugs
Type
article
Field-Weighted Citation Impact
17.32
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Exploring safe practice when handling cytotoxic drugs: findings from survey of UK cancer nurses

Karen Campbell, Daniel Dicksit
3 citations
Cancer Nursing Practice
Safe Handling of Antineoplastic Drugs
17.32
article

Exploring safe practice when handling cytotoxic drugs: findings from survey of UK cancer nurses

Karen Campbell, Daniel Dicksit
article en
3 citations

Abstract

Background Cytotoxic drugs, including chemotherapy, potentially pose significant risks to cancer nurses. Therefore, it is important to take measures to protect them from the health effects associated with these drugs. Aim To determine UK cancer nurses’ perceptions and experiences regarding potential exposure to cytotoxic drugs, including their knowledge of hazards, use of personal protective equipment (PPE) and closed system transfer devices (CSTDs), and perceived health effects. Method A cross-sectional survey was conducted across the UK, facilitated through the UK Oncology Nursing Society. Descriptive analyses were employed. Results The survey revealed that the PPE predominantly used by respondents when administering cytotoxic drugs were plastic aprons (97%, n=723/747) and either gloves labelled for use with chemotherapy (62%, n=466/747) or other gloves (53%, n=393/747). Around 70% (n=521/747) of respondents had used CSTDs during administration. Perceived health effects associated with handling cytotoxic drugs were reported by 161 respondents. Conclusion This study indicates that most cancer nurses have a high level of knowledge of the hazards of cytotoxic drugs, and that plastic aprons and gloves are the primary protection used against occupational exposure. However, there appear to be variation in their use of CSTDs. Many cancer nurses perceive their health to be compromised due to the handling of cytotoxic drugs. It is recommended that all cancer treatment settings across the UK should implement CSTDs.

Cancer Nursing PracticeVol. 25(2)
Edinburgh Napier University (GB)
Good health and well-being
Openalex Percentile: Top 1%
Safe Handling of Antineoplastic Drugs
17.32
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.