Study on cellular behavior and molecular mechanism of periodontal tissue in vitro

Periodontal regeneration is the ultimate goal of periodontal therapy. In the study of constructing periodontal tissue in vitro, attempts are made to simulate the regeneration process of periodontal tissue. The research and clinical application of periodontal ligament stem cells have made many breakthroughs, but they still face many challenges. To achieve true periodontal tissue regeneration, in-depth research on its molecular mechanism and signaling pathway is still needed. Combined with the research progress in recent years, this paper discusses the challenges and possible solutions faced in the process of periodontal tissue regeneration.