Mechanistic insights into EIF6 as a target of Apigenin in alleviating chondrocyte senescence
Apigenin upregulates EIF6 expression and mitigates H2O2-induced chondrocyte senescence, highlighting its potential as a therapeutic agent for KOA. These findings provide insights into the nutritional health benefits of Apigenin and its implications for KOA treatment.
Authors
- Peng Xu (ORCID: https://orcid.org/0000-0001-8007-9879)
- Hui Yu (ORCID: https://orcid.org/0000-0001-5249-0193)
- Zhi Yang (ORCID: https://orcid.org/0000-0003-2084-5193)
- Erliang Li
- Mingyi Yang (ORCID: https://orcid.org/0000-0001-8640-9795)
- Min Wang (ORCID: https://orcid.org/0000-0002-2479-6096)
- Xin Xu (ORCID: https://orcid.org/0009-0002-3960-9801)
Institutions
- Xi'an Honghui Hospital (CN)
- Arthritis Treatment Center (US)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Experimental Gerontology
- Published
- 2025-03-04
- DOI
- https://doi.org/10.1016/j.exger.2025.112725
- Primary Topic
- Flavonoids in Medical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00