Effects of time, anticoagulant and detection channel on platelet count in ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia

Our data showed that time, anticoagulant and detection channel significantly affected the PLT count in the EDTA-PTCP samples. For the EDTA-PTCP samples, the simplest retest method was to use the PLT-O channel of the Mindray automatic blood analyser within 30 min. In addition, changing the sodium citrate anticoagulant and using the XN-9100 PLT-F channel within 15 min were also suitable for correcting the spurious low PLT of the EDTA-PTCP samples.

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Publication Details

Journal
PeerJ
Published
2025-03-04
DOI
https://doi.org/10.7717/peerj.19103
Primary Topic
Clinical Laboratory Practices and Quality Control
Type
article
Field-Weighted Citation Impact
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article

Effects of time, anticoagulant and detection channel on platelet count in ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia

Jie Feng, Yuting Wen, Meifen Li, Meina Yan et al.
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PeerJ
Clinical Laboratory Practices and Quality Control
article

Effects of time, anticoagulant and detection channel on platelet count in ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia

Jie Feng, Yuting Wen, Meifen Li, Meina Yan, Guanghua Zhai, Wei Liang, Bei Chen, Liang Yu
article en

Abstract

Our data showed that time, anticoagulant and detection channel significantly affected the PLT count in the EDTA-PTCP samples. For the EDTA-PTCP samples, the simplest retest method was to use the PLT-O channel of the Mindray automatic blood analyser within 30 min. In addition, changing the sodium citrate anticoagulant and using the XN-9100 PLT-F channel within 15 min were also suitable for correcting the spurious low PLT of the EDTA-PTCP samples.

PeerJVol. 13
Suzhou Municipal Hospital (CN), Nanjing Medical University (CN), Nanjing University (CN)
Openalex Percentile: Top 95%
Clinical Laboratory Practices and Quality Control
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