Exercise-induced Activation of SIRT1/BDNF/mTORC1 Signaling Pathway: A Novel Mechanism to Reduce Neuroinflammation and Improve Post-stroke Depression
Exercise intervention reduces post-stroke depression-like behavior by activating SIRT1/BDNF/mTORC1 signaling pathway and reducing neuroinflammation. These findings provide insights into understanding the role of exercise in treating post-stroke depression and offer a theoretical basis for developing novel antidepressant strategies.
Authors
- Jin-Ling Tang (ORCID: https://orcid.org/0000-0002-4516-8179)
- Jie Yuan (ORCID: https://orcid.org/0000-0002-1150-8462)
- Lin Feng (ORCID: https://orcid.org/0000-0001-6461-5838)
- Lina Lü
Institutions
- Harbin University (CN)
- Heilongjiang University of Chinese Medicine (CN)
- First Affiliated Hospital of Heilongjiang University of Chinese Medicine (CN)
Publication Details
- Journal
- Actas Españolas de Psiquiatría
- Published
- 2025-03-05
- DOI
- https://doi.org/10.62641/aep.v53i2.1838
- Citations
- 6
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 7.34