A Case of Semaglutide-Induced Skin Burning

We discuss a case of semaglutide-induced skin burning in an 86-year-old patient. The skin burning stopped with withdrawal of semaglutide and reoccurred when semaglutide was rechallenged a few months later. The patient received multiple other glucagon-like peptide 1 receptor agonists and did not experience this reaction. As the use of GLP-1 therapies increase, it will be important to recognize and manage unique adverse events that may arise.